Eosinophilic esophagitis.

Mast Cells Distinguish Eosinophilic Esophagitis in Pediatric Patients.

BACKGROUND: Mast cells exert a substantial role in gastrointestinal allergic diseases. Therefore, it is reasonable to presume that mast cell may aid diagnosis in eosinophilic gastroenteropathy. OBJECTIVE: To evaluate whether mast cell count in the esophageal epithelium can discriminate eosinophilic esophagitis, proton-pump inhibitor (PPI)-responsive eosinophilic esophagitis and gastroesopha...

Eosinophilic esophagitis in adults is associated with IgG4 and not mediated by IgE.

BACKGROUND & AIMS Eosinophilic esophagitis is usually triggered by foods, by unclear mechanisms. We evaluated the roles of IgE and IgG4 in the development of eosinophilic esophagitis. METHODS We performed a prospective, randomized, double-blind, placebo-controlled trial of adults with eosinophilic esophagitis given an antibody against IgE (omalizumab, n = 16) or placebo (n = 14) every 2-4 wee...

Esophagitis dissecans associated with eosinophilic esophagitis in an adolescent

Esophagitis dissecans superficialis and eosinophilic esophagitis are distinct esophageal pathologies with characteristic clinical and histologic findings. Esophagitis dissecans superficialis is a rare finding on endoscopy consisting of the peeling of large fragments of esophageal mucosa. Histology shows sloughing of the epithelium and parakeratosis. Eosinophilic esophagitis is an allergic disea...

Dietary Treatment of Eosinophilic Esophagitis

Barrett's esophagus, reflux esophagitis, and eosinophilic esophagitis.

o r t R s h m f 3 o b Many new and exciting endoscopy-related studies on Barrett’s esophagus, reflux esophagitis, and eosinophilic esophagitis were presented during the 2012 Digestive Disease Week (DDW; 19-22 May, San Diego, California, USA). Endoscopic research in Barrett’s esophagus mainly focused on surveillance, detection, and ablation therapy, while clinical studies in eosinophilic esophag...

Eosinophilic Esophagitis: from Physiopathology to Treatment

Eosinophilic esophagitis is a chronic inflammatory disease characterized by eosinophilic infiltration of the esophageal mucosa. Food and aero-allergens are involved in its pathogenesis. Dysphagia and food impaction are the dominant symptoms in adult with eosinophilic esophagitis. However, a wide range of symptoms has been noticed such as chest pain or gastro-esophageal reflux disease-like sympt...